Karyopharm plummets as Xpovio fails in phase 3 trial for endometrial cancer


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  • Karyopharm Therapeutics (KPTI) is down ~69% in after-hours trading after reporting that Xpovio (selinexor) missed its primary goal in a phase 3 trial for endometrial cancer.
  • There was no significant difference in progression-free survival between patients with TP53 wild-type advanced



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