Netflix’s Cold Case franchise has cracked open the vault on some of the most haunting unsolved stories in recent years—and it is just getting started. From American Manhunt: The Boston Marathon Bombing to Missing: Dead or Alive, these titles do not just revisit past crimes—they unravel them. These shows probe deep into the dark spaces, where truth hides behind headlines and suspects vanish into thin air. Now, Netflix teases yet another spine-tingling tale, enveloped by rumors of danger and corporate faith betrayed. The clues? Scattered. The consequences? Lasting. And this one hits frighteningly close to home.
Like a breadcrumb trail scattered across time, this new documentary follows panic, poison, and a product once found in every home. What starts with a trusted name quickly dissolves into a national nightmare. The facts, the fear, and the faces involved—here are the details of the documentary that earns the documentary a spot on Netflix’s 2025 lineup!
The Date to watch for the next big cold case on Netflix
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Netflix’s Tudum has announced that Cold Case: The Tylenol M—— will be available to stream starting May 26. This gripping three-part docuseries is the newest addition to the Cold Case franchise, following the success of the 2024 JonBenét Ramsey investigation.

The series takes viewers through fresh interviews and new clues, revealing layers of this decades-old case. For anyone chasing terrifyingly gripping true crime documentaries to stream on Netflix in 2025, this one is sure to crack the top of the must-watch list. Do not miss May 26—it is the date to dive into one of the most haunting mysteries ever.
The docuseries delivers more than just dates and facts. And here is a closer look at what really happened when everyday medicine turned homicidal.
A poisoned past comes back into focus
Seven surprise fatalities, one horrifying connection- poisoned Tylenol capsules. The 1982 case that shook America and changed the way the nation trusted everyday medicine. That is the mystery at the heart of Netflix’s Cold Case: The Tylenol M——, coming in three episodes packed with new theories and chilling interviews.
Directed by Yotam Guendelman and Ari Pines, the unanswered questions are explored. Was it a single killer or a bigger conspiracy? Executive producer Joe Berlinger, known for his work on other Cold Case installments, guides viewers through unsettling evidence and fresh viewpoints that challenge what was previously believed.
Moving from story to screen, the trailer translates the complex case into gripping visuals and haunting sounds. Here is a first look at the intensity, the voices and scenes that add urgency and drive the investigation forward.
Ghosts the trailer summons from the Tylenol homicides
Starting with a chilling flashback, “I was eight years old,” the haunting soundtrack of the trailer pulls listeners into a tangled true crime story. What is behind those six poison-filled capsules? How do three victims’ lives connect in this web of fear? Police footage and newspaper headlines flash, hinting at a deeper truth.
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James Lewis looms large—a wanted man, the FBI’s obsession, and maybe a red herring. But is he the whole story or just the start? The trailer ends with a challenge echoing- “Follow the evidence wherever it takes you.” Coming soon to Netflix, this twisted tale is real horror, forgotten clues, and a date that is now marked on every true crime fan’s calendar. The case reopens not with answers, but with more questions—and a story that refuses to stay buried.
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Will Cold Case: The Tylenol M—— make it to your Netflix watchlist? Let us know in the comments.