A man has been charged with murder after an alleged fatal stabbing at a remote campsite in the NSW New England region.

Emergency services were called to the Woolbrook campsite off Danglemah Road, north of Tamworth, at about 6pm on Sunday.

Police were told two men were involved in an altercation when one was allegedly stabbed multiple times in the chest and neck.

The man, aged in his 50s, was treated by paramedics but could not be revived. He is yet to be formally identified.

The other man, aged 43, was uninjured. He was arrested at the campsite and taken to Tamworth Police Station, where he has since been charged with murder.

He will appear in Bail Division Court 5 later on Monday. 

Police allegedly seized a knife believed to have been used in the altercation.

The campsite remains a crime scene as detectives launch an investigation.

A man was allegedly stabbed to death at the Woolbrook campsite north of Tamworth on Sunday night

The campsite is in the NSW New England region, 443km north-west of Sydney

Inquiries are ongoing, with police scheduled to provide a further update later on Monday.

Located 66km north-east of Tamworth, Woolbrook is a free camping ground along the Macdonald River.

The secluded spot is ideal for tents, with only a few spots for caravans. The site also has no mobile phone coverage. 

The latest incident comes a week after an alleged axe murder at the Little Styx River campsite, about 147km away near Ebor.

Ahwen Kohn, 26, was refused bail when he faced court last week.

Rimani Pena Hughes, 33, had been camping at the Little Styx River Campground on Point Lookout Road on March 1 when he was allegedly attacked by Kohn.

A 25‑year‑old woman drove Mr Hughes to nearby Thora seeking help, but he died before paramedics arrived. 

The woman was treated for bruising to her neck after she was also allegedly assaulted.